Characteristics of Patients Presenting with Major Discordance (DS Moving from DS3 to DS4 and Vice Versa) Between PSF and PSFEARL
| i-PET | EoT-PET | |||||||
| Parameter | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 7 | Patient 8 |
| Characteristics | ||||||||
| Age (y) | 59 | 62 | 64 | 65 | 63 | 81 | 71 | 71 |
| Sex | F | F | F | M | F | F | M | M |
| Body mass index (kg/m2) | 31.2 | 30.8 | 22.1 | 28.7 | 38.1 | 28.5 | 33.8 | 26.7 |
| Ann Arbor stage | IV | III | IV | III | II | IV | III | IV |
| LDH | >Normal | ≤Normal | >Normal | ≤Normal | ≤Normal | >Normal | >Normal | >Normal |
| ECOG Performance status | 2 | 0 | 2 | 0 | 0 | 2 | 2 | 2 |
| Extranodal involvement | 1 | 0 | 4 | 0 | 0 | 2 | 3 | 1 |
| Age-adjusted IPI | 3 | 1 | 3 | 1 | 0 | 3 | 3 | 3 |
| Bulky disease | No | No | No | No | No | Yes | Yes | No |
| Follow-up | ||||||||
| Progression | No | No | Yes (5-mo delay) | No | No | Yes (16-mo delay) | No | No |
| Location of progression | Meningeal | Right axillary node | ||||||
| Death (delay) | No | No | Yes (9-mo delay) | No | No | No | No | No |
| PET data | ||||||||
| Location of initial mass | Anterior renal fascia | Mesenteric mass | L external iliac node | R cervical node | Supraclavicular node | R inguinal node | Mesenteric mass | L cervical node |
| Initial SUVlesion PSF/PSFEARL | 37.93/29.39 | 31.39/25.64 | 18.42/15.54 | 16.40/12.94 | 15.15/9.85 | 27.12/18.02 | 30.87/24.82 | 48.53/31.66 |
| Location of residual mass | L pleura | Mesenteric node | Pericardium | R cervical node | Anterior mediastinum | R axillary node | Mesenteric mass | Celiac node |
| Size of residual mass (mm) | 27 | 11 | 7 | 20 | 21 | 6 | 62 | 20 |
| SUVlesion PSF/PSFEARL | 4.61/3.26 | 4.21/3.29 | 4.01/2.79 | 4.36/2.86 | 4.82/3.85 | 3.93/2.49 | 4.12/2.90 | 3.31/2.66 |
| SUVliver PSF/PSFEARL | 4.02/3.35 | 3.96/3.45 | 3.59/3.12 | 4.23/3.32 | 4.88/3.58 | 3.58/3.04 | 3.85/3.22 | 3.29/2.75 |
| SUVmediastinum PSF/PSFEARL | 2.71/2.21 | 3.08/2.69 | 2.66/2.11 | 2.86/2.31 | 3.12/2.63 | 2.27/2.07 | 2.46/2.13 | 2.22/1.85 |
| DS–status PSF | 4, NR | 4, NR | 4, NR | 4, NR | 3, R | 4, NR | 4, NR | 4, NR |
| DS–status PSFEARL | 3, R | 3, R | 3, R | 3, R | 4, NR | 3, R | 3, R | 3, R |
| PSF ΔSUVmax | 87.8 | 86.6 | 78.2 | 73.4 | 68.2 | |||
| PSFEARL ΔSUVmax | 88.9 | 87.2 | 82.0 | 77.9 | 60.9 | |||
LDH = lactate dehydrogenase; ECOG = Eastern Cooperative Oncology Group; IPI= international prognostic index; R = responder; NR = nonresponder.