TABLE 1

Quantitative Measures of Reference Sphere in Healthy Liver Tissue Using TOF OSEM and BSREM

BSREM
MeasureTOF OSEM*β-factor, 133β-factor, 267β-factor, 400β-factor, 533
Volume (cm3)19.2 (18.0–19.6)
SUVmax2.9 (2.1–4.0)4.2 (2.7–5.4)3.1 (2.2–4.0)2.8 (2.0–3.7)2.6 (2.0–3.5)
SUVmean2.1 (1.6–2.6)2.0 (1.6–2.5)2.0 (1.6–2.5)2.1 (1.6–2.6)2.1 (1.6–2.6)
SUVSD0.2 (0.2–0.4)0.4 (0.3–0.6)0.3 (0.2–0.4)0.2 (0.2–0.3)0.2 (0.1–0.3)
Noise level*0.11 (0.09–0.16)0.22 (0.18–0.28)0.13 (0.11–0.17)0.10 (0.08–0.13)0.09 (0.07–0.11)
  • * Measured in liver and defined as SUVSD divided by SUVmean.

  • Data are mean followed by range. TOF OSEM used 3 iterations, 16 subsets, 5-mm gaussian postprocessing filter, and PSF. BSREM included TOF and PSF with β-factors of 133, 267, 400, and 533; 70-cm FOV; and 3 min/bp.