11C-erlotinib before elacridar | 11C-erlotinib after elacridar | ||||||
Patient no. | K1 | K2 | VT | K1 | K2 | VT | VT ratio |
1 | 0.012 | 0.030 | 0.395 | 0.011 | 0.036 | 0.312 | 0.790 |
2 | 0.015 | 0.090 | 0.167 | 0.013 | 0.066 | 0.198 | 1.186 |
3 | —* | —* | —* | 0.014 | 0.080 | 0.179 | —* |
4 | 0.010 | 0.060 | 0.160 | 0.017 | 0.076 | 0.221 | 1.381 |
5 | 0.12 | 0.100 | 0.128 | 0.014 | 0.123 | 0.116 | 0.906 |
Mean ± SD | 0.012 ± 0.002 | 0.070 ± 0.032 | 0.213 ± 0.123 | 0.014 ± 0.002 | 0.076 ± 0.031 | 0.205 ± 0.071 | 1.066 ± 0.268 |
↵* Data were excluded because peak uptake was missed during first scan.
Ratio is based on patients evaluable in both scans.