TABLE 1

Ex Vivo Biodistribution

	Control			DSS
Site	Mean	SD	n	Mean	SD	n
MLN	0.37	0.25	8	1.09^*	0.58	8
Colon	0.45	0.12	8	1.75^‡	0.40	8
Cecum	0.35	0.09	8	1.09^†	0.38	8
Small int.	5.12	1.33	8	4.87	1.13	8
Stomach	0.53	0.13	8	0.37^*	0.07	8
Thymus	0.17	0.14	8	0.16	0.11	8
Spleen	6.89	0.98	8	7.56	1.38	8
ALN	0.41	0.14	8	0.45	0.17	8
ILN	0.31	0.09	8	0.46^*	0.07	8
Blood	0.28	0.08	8	0.22	0.08	8
Liver	9.84	2.64	8	13.37	1.01	8
Kidney	23.84	6.26	8	27.30	3.68	8
Heart	0.15	0.04	8	0.21	0.07	8
Lung	0.38	0.26	8	0.36	0.03	8
Muscle	0.04	0.01	8	0.05	0.01	8
Femur	0.69	0.17	8	0.49	0.10	8
Tail	4.19	3.63	8	3.25	0.72	8
Carcass	19.53	3.24	8	16.64	0.96	8

↵* P < 0.05.
↵† P < 0.005.
↵‡ P < 0.0001.
Int. = intestine; ALN = axillary LN; ILN = inguinal LN.
Data are total activity (%ID) present in blood and organs from DSS-treated mice compared with control mice 26 h after injection of ⁸⁹Zr-malDFO-GK1.5 cDb.