TABLE 1

Baseline Patient Characteristics

CharacteristicData
Age (y)64 (55.7–71.0)
Sex
 Male217 (59)
 Female149 (41)
Primary tumor
 Colorectal cancer128 (35.0)
 Hepatocellular cancer57 (15.6)
 Neuroendocrine tumor51 (13.9)
 Metastatic breast cancer40 (10.9)
 Cholangiocarcinoma35 (9.6)
 Other*55 (15.0)
Hepatic tumor burden
 25%191 (52.2)
 25%–50%140 (38.3)
 50%35 (9.6)
Extrahepatic disease
 Yes253 (69.1)
 No113 (30.9)
Baseline liver function
 Bilirubin (mg/dL)0.6 (0.5–0.9) (reference range < 1.2)
 Cholinesterase (U/L)6.35 (4.89–7.6) (reference range > 4.6)
  • * Pancreas (n = 13), uveal melanoma (n = 6), gastric cancer (n = 6), sarcoma (n = 4), urothelial carcinoma (n = 4), ovarian cancer (n = 3), malignant melanoma (n = 3), cancer of unknown primary (n = 2), prostate cancer (n = 2), lung cancer (n = 2), thymus cancer (n = 2), base-of-tongue cancer (n = 2), squamous cell carcinoma (n = 1), endometrial cancer (n = 1), esophageal carcinoma (n = 1), thyroid carcinoma (n = 1), squamous cell carcinoma of maxillary sinus (n = 1), and testicular cancer (n = 1).

  • Qualitative data are expressed as numbers followed by percentages in parentheses; continuous data are expressed as median followed by interquartile range in parentheses.