TABLE 1

Sample Characteristics

CharacteristicControlMDD nonremitterMDD remitterP
Sample size311412
Age (y)32.62 ± 11.2737.03 ± 13.4736.67 ± 13.480.54*
HDRS-24 pretreatment1.68 ± 2.4125.43 ± 2.2624.08 ± 6.230.59
HDRS-24 posttreatment17.57 ± 3.905.33 ± 3.060.001
HDRS-17 scores (inclusion criteria)1.42 ± 1.2819.07 ± 4.6019.08 ± 5.031.0
Beck Depression Inventory1.29 ± 1.6926.71 ± 10.0422.42 ± 10.470.30
Beck Hopelessness Scale1.32 ± 1.8711.36 ± 5.257.8 ± 6.380.26
Age of onset25.5 ± 13.524.17 ± 12.610.66
Number of depressive episodes13.85 ± 30.5019.33 ± 37.470.69
Number of first-degree relatives with depression4 ± 24 ± 23 ± 20.48*
Percentage with comorbid anxiety7%8%0.96
Percentage female52%71%58%0.47
Percentage of smokers6.5257.10.25*
Free fraction (fP)0.12 ± 0.30.1 ± 0.010.1 ± 0.020.02*
Reference region binding10.50 ± 2.1910.64 ± 1.419.41 ± 1.390.07*
  • * Statistics comparing all groups.

  • Statistics comparing nonremitters and remitters, only.