TABLE 2

Parameter Values Used for the Presented Simulations

ParameterValue
Administered activity300 MBq of 211At
Administered fluid1.7 L of icodextrin
Fraction of labeled mAbs1 in 200 mAbs radiolabeled
D14 μm2s−1 (21)
f (fraction fluid in tumor)0.1 (11) (cell-packing ratio, 1 − f)
t0.5 s
x5 or 10 μm
kon44,000 M−1s−1 (4)
koff0
Antigens per cell700,000 (4)