TABLE 2

Regional ¹¹C-MeNER BP_ND in PD Patients and Healthy Subjects

		SRTM2			MRTM2
Brain region	Group	BP_ND	Relative reduction	P^*	BP_ND	Relative reduction	P^*
Nucleus ruber	HC	0.64 ± 0.22	31.71	0.002	0.70 ± 0.19	26.92	0.015
	PD	0.44 ± 0.15			0.51 ± 0.22
Median raphe	HC	0.52 ± 0.25	14.34	0.458	0.66 ± 0.31	13.37	0.498
	PD	0.44 ± 0.27			0.57 ± 0.34
Thalamus	HC	0.48 ± 0.15	29.50	0.008	0.54 ± 0.14	28.85	0.004
	PD	0.34 ± 0.10			0.39 ± 0.10
LC	HC	0.15 ± 0.20	44.26	0.295	0.26 ± 0.22	27.72	0.355
	PD	0.08 ± 0.12			0.19 ± 0.17
Hypothalamus	HC	0.23 ± 0.12	48.49	0.104	0.33 ± 0.20	44.78	0.056
	PD	0.12 ± 0.11			0.18 ± 0.20

↵* P values were corrected for multiple comparisons with Bonferroni adjustment: overall group effect at P = 0.040 for SRTM2 estimates and P = 0.043 for MRTM2 estimates.
HC = healthy control.
Data are regional mean BP_ND ± SD.