Key In Vivo Parameters
| Parameter | 18F-RO6958948 | 11C-RO6931643 | 11C-RO6924963 |
| SUVpeak | 2.0 | 1.2 | 1.9 |
| K1 (mL/mL/min) | 0.70 ± 0.20 | 0.10 ± 0.01 | 0.49 ± 0.06 |
| Ratio SUVpeak vs. SUV at 60 min after injection | 11.8 ± 4.3 | 3.3 ± 0.4 | 1.8 ± 0.1 |
| VT (mL/mL) | 6.4 ± 0.4 | 0.7 ± 0.1 | 29.1 ± 2.8 |
VT = total distribution volume.