TABLE 1

Characteristics at Diagnosis in Patients with 123I-MIBG–avid, Stage 4 Disease

Characteristicn
Total patients345
Sex
 Male212 (61%)
 Female133 (39%)
Age
 Median age2.9 (range, 0.2%–16.1%)
 Age < 18 mo48 (14%)
 Age ≥ 18 mo297 (86%)
MYCN status
 Amplified122 (35%)
 Nonamplified182 (53%)
 Unknown41 (12%)
ASCT261 (76%)
Chimeric antibody23 (7%)
  • ASCT = autologous stem cell transplantation, which was performed if patient was in CR/PR with ≤ 3 123I-MIBG–avid sites and > 50% reduction of 123I-MIBG–avid osseous lesions.