TABLE 1

Baseline Characteristics of 274 GEP NET Patients

Patients (n)
CharacteristicYesNo
Male139 (51)135 (49)
Age ≥ 70 y52 (19)222 (81)
Karnofsky performance status ≤ 7038 (14)236 (86)
Elevated chromogranin A level72 (26)202 (74)
Bone metastases59 (22)215 (78)
Patients who met inclusion criteria252 (92)22 (8)
Previous therapy
 Chemotherapy26 (10)248 (90)
 Radiotherapy (external)18 (7)256 (93)
NET location
 Gastrointestinal172 (63)
 Pancreas86 (31)
 Bronchus16 (6)
Tumor uptake on baseline [111In-DTPA0]octreotide scan
 Less than normal liver8 (3)
 Equal to or higher than normal liver203 (74)
 Higher than kidneys63 (23)
Tumor mass on baseline [111In-DTPA0]octreotide scan
 Limited and moderate223 (81)
 Extensive51 (19)
Cumulative administered activity*
 ≤22.2 GBq73 (27)
 22.3–29.6 GBq122 (44)
 29.7–44.4 GBq71 (26)
 44.5–59.2 GBq8 (3)
Age range at first treatment
 15–29 y1 (0.5)
 30–44 y31 (11.5)
 45–59 y109 (40)
 60–74 y110 (40)
 75–89 y23 (8)
  • * 177Lu-DOTATATE.

  • Data in parentheses are percentages.