Comparison of Tumor-to-Blood and Tumor-to-Muscle Ratios at 1, 6, and 24 Hours After Administration of 64Cu-NOTA-rEgA, 64Cu-DOTA-rEgA, or 64Cu-DTPA-rEgA to H1650 Tumor–Bearing Mice
Ratio | 64Cu-NOTA-rEgA | 64Cu-DOTA-rEgA | 64Cu-DTPA-rEgA |
Tumor-to-blood | |||
1 h | 3.50 ± 0.50 | 3.71 ± 0.95 | 2.57 ± 1.26 |
6 h | 5.00 ± 0.77 | 4.25 ± 2.12 | 6.01 ± 2.57 |
24 h | 4.58 ± 1.19 | 5.39 ± 1.11 | 4.76 ± 0.91 |
Tumor-to-muscle | |||
1 h | 8.96 ± 2.72 | 9.74 ± 1.40 | 4.71 ± 1.72 |
6 h | 16.38 ± 1.79 | 13.35 ± 2.32 | 13.95 ± 6.22 |
24 h | 10.55 ± 1.14 | 8.90 ± 1.43 | 11.09 ± 3.36 |