TABLE 4

Individual Management Changes

Management changeQ1 to Q2Q2 to implementedQ1 to implemented
Conversion to focal treatment/new focal treatment40 (40)14 (14)29 (29)
 Active surveillance to surgery ± ADT5 (5)0 (0)5 (5)
 Active surveillance to SRT ± ADT9 (9)2 (2)3 (3)
 Active surveillance to SBRT ± ADT0 (0)0 (0)1 (1)
 ADT to surgery ± ADT3 (3)0 (0)1 (1)
 ADT to surgery + SRT + ADT0 (0)0 (0)1 (1)
 ADT to SRT ± ADT4 (4)1 (1)2 (2)
 ADT to SRT + CTx + ADT1 (1)0 (0)0 (0)
 ADT to SBRT ± ADT4 (4)0 (0)4 (4)
 ADT to SBRT + CTx + ADT0 (0)0 (0)1 (1)
 CTx + ADT to surgery1 (1)0 (0)0 (0)
 CTx + ADT to SRT ± ADT1 (1)1 (1)1 (1)
 CTx + ADT to SBRT ± ADT1 (1)0 (0)2 (2)
 PSMA-RNT to SRT + ADT0 (0)1 (1)0 (0)
 SRT ± ADT to surgery5 (5)2 (2)2 (2)
 SRT ± ADT to SBRT ± ADT5 (5)1 (1)5 (5)
 SRT ± ADT to SBRT + SRT ± ADT0 (0)1 (1)1 (1)
 SRT ± ADT to SBRT + CTx + ADT0 (0)1 (1)0 (0)
 SRT + CTx + ADT to SBRT + ADT0 (0)1 (1)0 (0)
 SBRT + ADT to surgery1 (1)0 (0)0 (0)
 Surgery + ADT to SRT + ADT0 (0)2 (2)0 (0)
 Surgery + ADT to surgery + SRT + ADT0 (0)1 (1)0 (0)
Conversion to systemic treatment12 (12)7 (7)13 (13)
 Active surveillance to ADT4 (4)1 (1)4 (4)
 Active surveillance to other systemic treatment + ADT0 (0)0 (0)3 (3)
 Surgery ± ADT to ADT0 (0)3 (3)0 (0)
 SRT + CTx ± ADT to ADT1 (1)0 (0)1 (1)
 SRT ± ADT to ADT5 (5)2 (2)5 (5)
 SRT ± ADT to CTx + ADT1 (1)0 (0)0 (0)
 SBRT + ADT to other systemic treatment + ADT1 (1)1 (1)0 (0)
 Unknown to ADT0 (0)0 (0)0 (0)
Conversion to active surveillance5 (5)7 (7)7 (7)
 Surgery ± ADT to active surveillance0 (0)3 (3)0 (0)
 SRT ± ADT to active surveillance4 (4)2 (2)4 (4)
 SRT + CTx to active surveillance0 (0)0 (0)0 (0)
 ADT to active surveillance1 (1)2 (2)3 (3)
Change in systemic treatment5 (5)7 (7)5 (5)
 ADT to CTx ± ADT3 (3)0 (0)0 (0)
 ADT to other systemic treatment ± ADT0 (0)4 (4)2 (2)
 CTx ± ADT to ADT0 (0)3 (3)1 (1)
 CTx + bone RNT + ADT to ADT + CTx0 (0)0 (0)0 (0)
 CTx + bone RNT + ADT to CTx + PSMA-RNT + ADT0 (0)0 (0)0 (0)
 CTx + bone RNT + ADT to PSMA-RNT1 (1)0 (0)1 (1)
 Bone RNT + ADT to CTx + ADT1 (1)0 (0)1 (1)
 Bone RNT + ADT to PSMA-RNT0 (0)0 (0)0 (0)
Total62 (61)35 (35)54 (53)
  • ADT = androgen deprivation therapy; SRT = salvage radiation therapy; SBRT = stereotactic body radiation therapy; CTx = chemotherapy; RNT = radionuclide therapy.

  • Data are numbers followed by percentages in parentheses.