TABLE 3

MBF and MFR Reference Ranges for 13N-Ammonia PET

PublicationSample size (n)Age (y)Stress agentRest MBF (mL/min/g)Stress MBF (mL/min/g)MFR
Hutchins et al. (212)724 ± 4Dipyridamole0.88 ± 0.174.17 ± 1.124.80 ± 1.30
Chan et al. (213)2035 ± 16Dipyridamole1.10 ± 0.204.33 ± 1.304.00 ± 1.30
Czernin et al. (67)1831 ± 9Dipyridamole0.76 ± 0.253.00 ± 0.804.1 ± 0.90
Czernin et al. (38)1127 ± 7DipyridamoleNR2.13 ± 0.28NR
Nagamachi et al. (21)3033 ± 15Dipyridamole/adenosine0.62 ± 0.142.01 ± 0.39NR
Yokoyama et al. (163)1456 ± 10Dipyridamole0.70 ± 0.172.86 ± 1.204.13 ± 1.38
Böttcher et al. (214)1024 ± 5Dipyridamole0.61 ± 0.091.86 ± 0.273.16 ± 0.80
Campisi et al. (215)1062 ± 6Dipyridamole0.68 ± 0.162.04 ± 0.303.16 ± 0.85
Nitzsche et al. (216)1528 ± 12Adenosine0.64 ± 0.092.63 ± 0.75NR
Dayanikli et al. (159)1148 ± 8Adenosine0.68 ± 0.802.64 ± 0.394.27 ± 0.52
Sawada et al. (73)636 ± 14Adenosine0.71 ± 0.122.49 ± 0.743.50 ± 0.69
Beanlands et al. (86)527 ± 4Adenosine0.62 ± 0.092.51 ± 0.274.10 ± 0.71
Muzik et al. (217)1026 ± 6Adenosine0.77 ± 0.163.40 ± 0.574.60 ± 0.90
Muzik et al. (88)2044 ± 11Adenosine0.67 ± 0.112.85 ± 0.494.28 ± 0.65
Lortie et al. (22)14NRDipyridamole0.69 ± 0.092.71 ± 0.504.25 ± 0.91
DeGrado et al. (218)8NRDipyridamole0.76 ± 0.172.68 ± 0.753.61 ± 1.06
Tawakol et al. (71)7NRAdenosine0.70 ± 0.193.51 ± 0.84NR
Schindler et al. (219)2137 ± 13Dipyridamole0.61 ± 0.122.04 ± 0.37NR
Quercioli et al. (70)2143 ± 11Dipyridamole0.71 ± 0.102.37 ± 0.493.38 ± 0.67
Valenta et al. (220)2638 ± 10Dipyridamole0.71 ± 0.132.29 ± 0.513.28 ± 0.70
Prior et al. (68)5042 ± 13Dipyridamole/adenosine0.64 ± 0.121.98 ± 0.443.40 ± 1.00
Renaud et al. (221)1431 ± 6Dipyridamole0.68 ± 0.122.86 ± 1.144.15 ± 1.57
Slomka et al. (27)15NRAdenosine0.85 ± 0.162.77 ± 0.653.39 ± 1.22
Weighted mean363 (total)37.60.712.583.54
  • NR = not reported.