TABLE 4

18F-FDG PET and CT Response at 3 Months Predict BOR

VariableAUCP
Guideline
 ΔSPD-Cheson0.95 (0.83–1.0)0.008
 PET 5-point scale0.80 (0.55–1.0)0.079
Intensity of glucose consumption within tumor volume
 ΔSUVmean0.89 (0.72–1.0)0.01
 ΔSUVmax0.87 (0.67–1.0)0.028
Tumor burden
 ΔMTV0.98 (0.90–1.0)0.005
 ΔTLG0.95 (0.86–1.0)0.003
Intensity of glucose consumption within healthy lymphoid tissue
 ΔSUVmax spleen0.85 (0.63–1.0)0.04
  • Responders had significant decrease in tumor volume and metabolism and increase in spleen metabolism at 3 mo. Data in parentheses are 95% confidence intervals.