18F-FDG PET and CT Response at 3 Months Predict BOR
Variable | AUC | P |
Guideline | ||
ΔSPD-Cheson | 0.95 (0.83–1.0) | 0.008 |
PET 5-point scale | 0.80 (0.55–1.0) | 0.079 |
Intensity of glucose consumption within tumor volume | ||
ΔSUVmean | 0.89 (0.72–1.0) | 0.01 |
ΔSUVmax | 0.87 (0.67–1.0) | 0.028 |
Tumor burden | ||
ΔMTV | 0.98 (0.90–1.0) | 0.005 |
ΔTLG | 0.95 (0.86–1.0) | 0.003 |
Intensity of glucose consumption within healthy lymphoid tissue | ||
ΔSUVmax spleen | 0.85 (0.63–1.0) | 0.04 |
Responders had significant decrease in tumor volume and metabolism and increase in spleen metabolism at 3 mo. Data in parentheses are 95% confidence intervals.