TABLE 3

Clinical Scenarios for SSTR PET

Scenario no.	Description	Appropriateness	Score
1	Initial staging after histologic diagnosis of NETs	Appropriate	9
2	Localization of primary tumor in patients with known metastatic disease but unknown primary	Appropriate	9
3	Selection of patients for SSTR-targeted PRRT	Appropriate	9
4	Staging NETs before planned surgery	Appropriate	8
5	Evaluation of mass suggestive of NET not amenable to endoscopic or percutaneous biopsy (e.g., ileal lesion, hypervascular pancreatic mass, mesenteric mass)	Appropriate	8
6	Monitoring of NETs seen predominantly on SSTR PET	Appropriate	8
7	Evaluation of patients with biochemical evidence and symptoms of NET without evidence on CI and without prior histologic diagnosis of NET	Appropriate	7
8	Restaging at time of clinical or laboratory progression without progression on CI	Appropriate	7
9	New indeterminate lesion on CI, with unclear progression	Appropriate	7
10	Restaging of patients with NETs at initial follow-up after resection with curative intent	May be appropriate	6
11	Selection of patients with nonfunctional NETs for SSA treatment	May be appropriate	6
12	Monitoring in patients with NETs seen on both CI and SSTR PET with active disease and no clinical evidence of progression	May be appropriate	5