TDR of Distant Metastasis and Synchronous Cancer for CXR/MRI of Head and Neck Versus 18F-FDG PET/CT in 307 HNSCC Patients
| HNSCC patients (n = 307) | PET/CT | CXR/MRI | Absolute difference in % | P |
| Distant metastasis | 18 (6%) | 3 (1%) | 5% (2%–8%) | <0.001 |
| Oral cavity (n = 147) | 8 (5%) | 1 (1%) | 5% (1%–9%) | 0.02 |
| Pharynx (n = 103) | 7 (7%) | 1 (1%) | 6% (0.1%–11%) | 0.03 |
| Larynx (n = 57) | 3 (5%) | 1 (2%) | 4% (−3%–10%) | 0.50 |
| Synchronous cancer | 25 (8%) | 3 (1%) | 7% (4%–10%) | <0.001 |
| Oral cavity (n = 147) | 13 (9%) | 1 (1%) | 8% (3%–13%) | <0.001 |
| Pharynx (n = 103) | 8 (8%) | 2 (2%) | 6% (0.1%–11%) | 0.03 |
| Larynx (n = 57) | 4 (7%) | 0 (0%) | 7% (−1%–15%) | 0.13 |
| Distant metastasis or synchronous cancer | 40 (13%) | 6 (2%) | 11% (7%–15%) | <0.001 |
| Oral cavity (n = 147) | 20 (14%) | 2 (1%) | 12% (6%–18%) | <0.001 |
| Pharynx (n = 103) | 14 (14%) | 3 (3%) | 11% (4%–18%) | 0.001 |
| Larynx (n = 57) | 6 (11%) | 1 (2%) | 9% (−0.1%–18%) | 0.06 |
Data in parentheses are 95% confidence intervals.