TABLE 2

Sensitivity, Specificity, and A_ROC for Detecting Global PET MFR Less Than 2 with SPECT MFR for Different Correction Approaches

	Global PET MFR < 2 (n = 9/29)
Correction	Threshold	Sensitivity	Specificity	Accuracy	A_ROC
−BB, −AC, −MC	2.15	1.00	0.70	0.79	0.882^*^,^†
+MC	1.54	0.89	1.00	0.97	0.975^*^,^†^,^‡
+AC, −MC	1.95	0.78	0.90	0.86	0.866
+MC	1.90	0.78	0.90	0.86	0.878^‡
+BB, −AC, −MC	1.53	0.78	1.00	0.93	0.934^†^,^‡
+MC	1.83	1.00	0.80	0.86	0.948^†^,^‡
+AC, −MC	1.78	0.78	0.95	0.90	0.897^‡
+MC	1.70	0.78	1.00	0.93	0.903^‡

↵* +MC vs. –MC for A_ROC, P < 0.004.
↵† +BB vs. –BB for A_ROC, P < 0.004.
↵‡ +AC vs. –AC for A_ROC, P < 0.004.
Threshold chosen to maximize sensitivity × specificity, using mean Renkin–Crone model parameters (Table 1).