TABLE 2

Sensitivity, Specificity, PPV, NPV, and Accuracy of 18F-PSMA-1007 PET/CT and mpMRI Compared with RP Specimen Histopathology

AgreementSensitivitySpecificityPPVNPVAccuracy
Total
18F-PSMA-1007 PET/CT71% (64%–77%)81% (75%–87%)83% (77%–88%)68% (61%–75%)75%
 mpMRI86% (79%–92%)64% (57%–71%)60% (52%–67%)88% (82%–93%)73%
 Combination81% (75%–86%)81% (73%–87%)85% (79%–90%)75% (68%–82%)81%
Near-total
18F-PSMA-1007 PET/CT93% (89%–96%)92% (87%–96%)94% (90%–97%)91% (86%–95%)93%
 mpMRI92% (87%–96%)83% (76%–88%)85% (79%–90%)91% (85%–95%)87%
 Combination89% (84%–93%)99% (95%–100%)99% (96%–100%)85% (78%–90%)93%
  • Data in parentheses are 95% CIs.