Sensitivity, Specificity, PPV, NPV, and Accuracy of 18F-PSMA-1007 PET/CT and mpMRI Compared with RP Specimen Histopathology
Agreement | Sensitivity | Specificity | PPV | NPV | Accuracy |
Total | |||||
18F-PSMA-1007 PET/CT | 71% (64%–77%) | 81% (75%–87%) | 83% (77%–88%) | 68% (61%–75%) | 75% |
mpMRI | 86% (79%–92%) | 64% (57%–71%) | 60% (52%–67%) | 88% (82%–93%) | 73% |
Combination | 81% (75%–86%) | 81% (73%–87%) | 85% (79%–90%) | 75% (68%–82%) | 81% |
Near-total | |||||
18F-PSMA-1007 PET/CT | 93% (89%–96%) | 92% (87%–96%) | 94% (90%–97%) | 91% (86%–95%) | 93% |
mpMRI | 92% (87%–96%) | 83% (76%–88%) | 85% (79%–90%) | 91% (85%–95%) | 87% |
Combination | 89% (84%–93%) | 99% (95%–100%) | 99% (96%–100%) | 85% (78%–90%) | 93% |
Data in parentheses are 95% CIs.