Characteristics of Extraosseous and Transosseous Meningiomas
| Parameter | Variable | Extraosseous (n = 15) | Transosseous (n = 67) | P |
| Age (y) | 55 (51–66) | 49 (47–61) | 0.073 | |
| Male sex | 6 (40%) | 13 (19%) | 0.087 | |
| Pathology | ||||
| WHO grade | I | 9 (60%) | 56 (84%) | NA |
| II | 6 (40%) | 9 (13%) | ||
| III | 0 (0%) | 2 (3%) | ||
| Histologic subtype | Transitional | 5 (38%) | 22 (38%) | NA |
| Meningothelial | 2 (15%) | 15 (26%) | ||
| Microcystic | 0 (0%) | 4 (7%) | ||
| Fibroblastic | 0 (0%) | 1 (2%) | ||
| Secretory | 0 (0%) | 5 (9%) | ||
| Atypical | 6 (46%) | 9 (16%) | ||
| Anaplastic | 0 (0%) | 2 (3%) | ||
| Qualitative imaging | ||||
| Meningiomatosis | 9 (60%) | 26 (39%) | 0.134 | |
| Location | Parasagittal/parafalcine | 5 (33%) | 10 (15%) | NA |
| Convexity | 6 (40%) | 12 (18%) | ||
| Sphenoid wing | 3 (20%) | 42 (63%) | ||
| Cerebellopontine | 0 (0%) | 2 (3%) | ||
| Suprasellar/parasellar | 1 (7%) | 1 (1%) | ||
| PET/CT for osseous involvement | No signs of | 13 (87%) | 0 (0%) | NA |
| Suggestive of | 0 (0%) | 1 (1%) | ||
| Consistent with | 2 (13%) | 66 (99%) | ||
| CE-MRI for osseous involvement | No signs of | 9 (60%) | 12 (18%) | NA |
| Suggestive of | 5 (33%) | 19 (28%) | ||
| Consistent with | 1 (7%) | 36 (54%) | ||
| Peritumoral edema | None | 8 (53%) | 33 (49%) | 0.858 |
| Mild | 3 (20%) | 18 (27%) | ||
| Extensive | 4 (27%) | 16 (24%) | ||
| Quantitative imaging | ||||
| Meningioma volume in PET/CT (mL) | 3.3 (1.6–4.7) | 12.8 (6.8–32.9) | <0.001* | |
| Meningioma volume in CE-MRI (mL) | 2.5 (1.4–4.7) | 10.6 (4.6–22.0) | 0.001* | |
| Meningioma SUVmax | 7.6 (4.3–13.9) | 14.2 (10.0–22.4) | 0.011* | |
| Meningioma SUVmean | 2.7 (1.9–3.0) | 4.3 (3.1–5.9) | 0.001* | |
| Pituitary SUVmax | 15.8 (12.9–20.0) | 15.7 (11.6–19.3) | 0.852 | |
| Pituitary SUVmean | 3.7 (3.5–4.2) | 4.0 (3.3–4.7) | 0.587 |
↵* Statistically significant.
WHO = World Health Organization; NA = not applicable.
Data are count followed by percentage for categoric variables and median followed by interquartile range for continuous variables. Proportion analysis was tested using χ2 test. Nonparametric testing for continuous variables was performed using Mann–Whitney U test.