TABLE 1

Tumor Volume, SUVmean, and SUVmax Before and After Treatment with Cediranib or Vehicle for 2 or 7 Days

Volume (mm3)SUVmeanSUVmax
Length of treatmentBeforeAfterBeforeAfterBeforeAfter
2 d
 Cediranib (n = 6)330 ± 63345 ± 530.52 ± 0.040.39 ± 0.080.96 ± 0.090.73 ± 0.18
  P0.670.01*0.03*
 Vehicle (n = 5)526 ± 378518 ± 4220.53 ± 0.050.49 ± 0.071.05 ± 0.151.00 ± 0.20
  P0.980.110.36
7 d
 Cediranib (n = 6)700 ± 297604 ± 2480.56 ± 0.170.38 ± 0.080.99 ± 0.320.71 ± 0.19
  P0.560.010.01*
 Vehicle (n = 4)577 ± 556931 ± 9820.58 ± 0.180.52 ± 0.211.07 ± 0.310.92 ± 0.46
  P0.550.400.30

  • ↵* Statistically significant.