Baseline Characteristics of Total Patient Population
| Characteristic | All patients (n = 4,057) | Normal SPECT (n = 3,137) | Abnormal SPECT (n = 920) | P | Small ischemic defect (n = 353) | Moderate/large ischemic defect (n = 222) | P | Small total defect (n = 558) | Moderate/large total defect (n = 362) | P |
| Age (y) | 61 ± 11 | 60 ± 11 | 64 ± 11 | <0.001 | 63 ± 10 | 64 ± 10 | 0.48 | 63 ± 11 | 64 ± 11 | 0.14 |
| Male sex | 1,717 (42) | 1,193 (38) | 524 (57) | <0.001 | 188 (53.3) | 122 (55.0) | 0.69 | 306 (55) | 218 (60) | 0.11 |
| BMI | 27.6 ± 4.8 | 27.3 ± 4.6 | 28.7 ± 5.4 | <0.001 | 29.5 ± 5.3 | 29.1 ± 5.3 | 0.39 | 28.9 ± 5.3 | 28.3 ± 5.5 | 0.11 |
| Diabetes | 543 (13) | 362 (12) | 181 (20) | <0.001 | 83 (23.5) | 50 (22.5) | 0.78 | 108 (19) | 73 (20) | 0.76 |
| Hypertension | 2,444 (60) | 1,861 (60) | 583 (63) | 0.03 | 247 (70.0) | 140 (63.1) | 0.09 | 366 (66) | 217 (60) | 0.08 |
| Hypercholesterolemia | 1,706 (42) | 1,299 (41) | 407 (44) | 0.13 | 167 (47.3) | 118 (53.2) | 0.17 | 240 (43) | 167 (46) | 0.35 |
| Current smoking | 644 (16) | 484 (15) | 160 (17) | 0.16 | 70 (19.8) | 33 (14.9) | 0.13 | 96 (17) | 64 (18) | 0.86 |
| Family history of CAD | 2,249 (56) | 1,752 (56) | 497 (54) | 0.33 | 194 (55.0) | 115 (51.8) | 0.43 | 318 (57) | 179 (50) | 0.02 |
| LBBB | 189 (4.7) | 75 (2.4) | 114 (12.4) | <0.001 | 25 (7.1) | 6 (2.7) | 0.03 | 77 (13.8) | 37 (10.2) | 0.11 |
Values are shown as number, with percentages in parentheses, or mean ± SD. Data are a comparison between patients with normal and abnormal SPECT MPI and a comparison between patients with small and moderate/large perfusion defects.