TABLE 2

Biodistribution of 10 pmol ⁹⁰Y-OPS201 and ¹¹¹In-OPS201 in Nude Mice Bearing HEK-hsstr2 Tumor Xenografts

	⁹⁰Y-OPS201			¹¹¹In-OPS201
Organ	4 h	24 h	72 h	4 h	72 h
Blood	0.07 ± 0.02	0.02 ± 0.00	0.01 ± 0.00	0.15 ± 0.02	0.00 ± 0.00
Heart	0.49 ± 0.15	0.12 ± 0.02	0.04 ± 0.01	0.22 ± 0.04	0.03 ± 0.00
Lung	8.81 ± 3.78	2.47 ± 0.43	1.38 ± 0.83	3.00 ± 1.45	0.32 ± 0.14
Liver	1.69 ± 0.50	0.72 ± 0.13	0.35 ± 0.11	0.64 ± 0.13	0.20 ± 0.02
Pancreas	46.3 ± 7.61	22.9 ± 1.70	5.18 ± 0.89	19.5 ± 4.29	0.93 ± 0.31
Spleen	0.98 ± 0.24	0.41 ± 0.08	0.31 ± 0.14	0.47 ± 0.08	0.16 ± 0.02
Stomach	46.1 ± 10.2	23.2 ± 2.56	9.83 ± 1.37	14.0 ± 1.73	1.53 ± 0.24
Intestine	11.2 ± 4.50	6.64 ± 0.52	2.50 ± 0.64	3.66 ± 1.78	0.57 ± 0.07
Adrenal	14.0 ± 2.26	7.21 ± 1.07	3.42 ± 0.75	3.62 ± 0.97	0.45 ± 0.10
Kidney	4.74 ± 1.07	4.31 ± 0.62	1.97 ± 0.35	7.29 ± 1.19	2.78 ± 0.40
Muscle	0.09 ± 0.06	0.04 ± 0.02	0.02 ± 0.01	0.09 ± 0.03	0.03 ± 0.01
Femur	1.09 ± 0.94	0.13 ± 0.11	0.20 ± 0.14	1.07 ± 0.75	0.14 ± 0.09
Salivary gland	2.39 ± 1.14	0.56 ± 0.07	0.19 ± 0.16	0.63 ± 0.31	0.06 ± 0.01
Tumor	17.9 ± 4.55	21.3 ± 7.86	7.41 ± 1.57	30.0 ± 4.56	12.8 ± 2.08

Data are %IA/g ± SD, n = 6–10.