TABLE 2

Clinical Scenarios in Which Cardiac PET May Be Useful in Suspected or Known CS

ScenarioSpecifics
Patients with histologic evidence of extraCS, and abnormal screening for CS, defined as one or more of following:Abnormal electrocardiographic findings of complete left or right bundle branch block or presence of unexplained pathologic Q waves in two or more leads
Echocardiographic findings of regional wall motion abnormality, wall aneurysm, basal septum thinning, or LVEF ≤ 50%
Holter findings of sustained or nonsustained ventricular tachycardia
Cardiac MRI findings suggestive of CS
Unexplained palpitations or syncope
Young patients (<60 y) with unexplained, new onset, significant conduction system disease (such as sustained second- or third-degree atrioventricular block)
Patients with idiopathic sustained ventricular tachycardia, defined as not fulfilling any of the following criteria:Typical outflow tract ventricular tachycardia
Fascicular ventricular tachycardia
Ventricular tachycardia secondary to other structural heart disease (coronary artery disease or any cardiomyopathy other than idiopathic)
Patients with proven CS as adjunct to follow response to treatment