Biodistribution of 11C-Sarcosine in Major Organs of Rats (%ID/g)
Organ | 5 min | 15 min | 30 min | 60 min | 90 min |
Brain | 0.090 ± 0.021 | 0.109 ± 0.014 | 0.138 ± 0.042 | 0.114 ± 0.031 | 0.115 ± 0.051 |
Eyeballs | 0.194 ± 0.034 | 0.212 ± 0.028 | 0.168138 ± 0.049 | 0.115 ± 0.030 | 0.111 ± 0.022 |
Heart | 0.462 ± 0.130 | 0.455 ± 0.028 | 0.325138 ± 0.040 | 0.217 ± 0.036 | 0.198 ± 0.049 |
Lung | 1.049 ± 0.126 | 1.159 ± 0.179 | 0.821138 ± 0.145 | 0.531 ± 0.056 | 0.467 ± 0.094 |
Liver | 1.291 ± 0.541 | 1.100 ± 0.354 | 1.013138 ± 0.417 | 0.633 ± 0.169 | 0.662 ± 0.159 |
Pancreas | 1.068 ± 0.618 | 1.218 ± 0.370 | 1.106 ± 0.153 | 1.045 ± 0.695 | 0.960 ± 0.551 |
Spleen | 0.626 ± 0.041 | 0.623 ± 0.125 | 0.493 ± 0.041 | 0.392 ± 0.011 | 0.398 ± 0.091 |
Adrenal | 0.620 ± 0.166 | 0.555 ± 0.021 | 0.503 ± 0.056 | 0.398 ± 0.153 | 0.474 ± 0.318 |
Kidney | 3.004 ± 1.114 | 2.776 ± 0.607 | 1.774 ± 0.362 | 1.260 ± 0.254 | 0.956 ± 0.129 |
Stomach | 1.032 ± 0.319 | 1.033 ± 0.074 | 0.861 ± 0.169 | 0.610 ± 0.097 | 0.541 ± 0.050 |
Ovary* | 0.863 ± 0.170 | 0.786 ± 0.031 | 0.727 ± 0.063 | 0.432 ± 0.004 | 0.375 ± 0.008 |
Uterus* | 0.724 ± 0.068 | 0.508 ± 0.200 | 0.447 ± 0.169 | 0.522 ± 0.220 | 0.181 ± 0.018 |
Testes* | 0.071 ± 0.054 | 0.172 ± 0.012 | 0.122 ± 0.007 | 0.114 ± 0.025 | 0.079 ± 0.001 |
Muscle | 0.140 ± 0.040 | 0.206 ± 0.015 | 0.224 ± 0.047 | 0.226 ± 0.067 | 0.164 ± 0.032 |
Bone | 0.752 ± 0.543 | 0.604 ± 0.071 | 0.506 ± 0.076 | 0.37 ± 0.038 | 0.265 ± 0.101 |
Blood | 0.396 ± 0.247 | 0.423 ± 0.028 | 0.245 ± 0.054 | 0.179 ± 0.034 | 0.196 ± 0.035 |
↵* n = 2 animals used for these values.