TABLE 2

Imaging Findings of Patients Included in Study

		¹⁸F-FDG PET/CT result
			Semiquantitative analysis (3D-SSP)^*
			Cortical regions with significant metabolic change
Patient no.	Antibody	Visual PET interpretation	Hypometabolism	Hypermetabolism	Interpretation	Brain MRI interpretation
1	Anti-NMDA	Abnormal	PAR (R, L), TMP (R), FRT (R, L), OCC (R, L)	—	Abnormal	Normal
2	Anti-NMDA	Abnormal	PAR (R, L), TMP (R, L), FRT (R, L), OCC (R, L)	—	Abnormal	Normal
3	Anti-NMDA	Abnormal	PAR (R, L), FRT (R, L), OCC (R, L)	—	Abnormal	Normal
4	Anti-NMDA	Abnormal	OCC (R)	—	Abnormal	Normal
5	Anti-NMDA	Abnormal	PAR (L), OCC (R, L)	—	Abnormal	Normal
6	Anti-VGKC	Abnormal	—	—	Normal	Normal
7	Anti-VGKC	Abnormal	PAR (R, L), TMP (L), FRT (R, L), OCC (L)	—	Abnormal	Abnormal
8	Anti-VGKC	Abnormal	PAR (R, L), FRT (R), OCC (R, L)	—	Abnormal	Normal
9	Anti-VGKC	Abnormal	PAR (R, L), TMP (R, L), FRT (R, L), OCC (R, L)	—	Abnormal	Abnormal
10	Anti-VGKC	Abnormal	PAR (R, L), TMP (R), FRT (R, L)	—	Abnormal	Abnormal
11	Anti-VGKC	Abnormal	PAR (L)	TMP (R), FRT (R), OCC (R)	Abnormal	Abnormal
12	Anti-Ma2	Abnormal	PAR (L), TMP (L), FRT (L), OCC (R, L)	—	Abnormal	Abnormal
13	Anti-Ma2	Abnormal	PAR (R, L), TMP (R, L), FRT (R, L), OCC (R, L)	—	Abnormal	Abnormal
14	Anti-Hu	Abnormal	PAR (R, L), FRT (R, L), OCC (R, L)	—	Abnormal	Normal
15	Anti-Hu	Abnormal	—	PAR (R, L), TMP (R, L), FRT (R, L), OCC (R, L)	Abnormal	Abnormal
16	Anti-Hu	Abnormal	FRT (R, L), OCC (R)	—	Abnormal	Normal
17	Anti-LGI1	Abnormal	PAR (R, L), TMP (R, L), FRT (R, L), OCC (R, L)	—	Abnormal	Normal
18	Anti-LGI1	Abnormal	PAR (R), TMP (R), FRT (R, L), OCC (R, L)	—	Abnormal	Abnormal
19	Anti-GAD65	Abnormal	PAR (R, L), FRT (R)	—	Abnormal	Abnormal
20	Anti-GAD65	Abnormal	PAR (R, L), FRT (R, L), OCC (L)	—	Abnormal	Normal
21	Anti-GAD65	Abnormal	PAR (R, L), OCC (R)	—	Abnormal	Abnormal
22	Antiialpha3ACHR	Abnormal	OCC (R, L)	—	Abnormal	Normal
23	Anti-alpha3ACHR	Abnormal	PAR (R, L), TMP (R, L), FRT (R, L), OCC (L)	—	Abnormal	Normal

↵* Average z score > 2 (2-tail P = 0.05) was considered as significant metabolic change. Bold regions represent areas with higher absolute z scores (absolute z > 2.58, 2-tail P = 0.01).
3D-SSP = 3D stereotactic surface projections; PAR = parietal cortex; TMP = temporal lobe; OCC = occipital lobe; FRT = frontal lobe.