Analysis of Prognostic Factors of OS
| Univariate analysis | Multivariate analysis | |||||
| Variable | Median OS (mo) | 95% CI | P | HR | 95% CI | P |
| Age (y) | 0.094 | |||||
| ≤65 | 19.1 | 9.8–28.4 | ||||
| >65 | 8.9 | 6.0–11.8 | ||||
| CEA (ng/mL) | 0.062 | |||||
| ≤5.0 | 18.4 | 15.8–21.0 | ||||
| >5.0 | 8.9 | 4.7–13.1 | ||||
| Initial SUVmax | 0.003 | 2.61 | 1.18–5.81 | 0.019 | ||
| ≤10.0 | 19.1 | 16.1–22.1 | ||||
| 10.0 | 10.9 | 3.8–18.1 | ||||
| SUVmax reduction (at best 18F-FDG PET response) | 0.074 | 1.96 | 0.91–4.20 | 0.082 | ||
| ≥20.0% | 20.7 | 5.8–35.6 | ||||
| 20.0% | 13.2 | 2.8–23.6 | ||||
| Organs with 18F-FDG uptake (n) | 0.039 | 2.08 | 0.95–4.57 | 0.068 | ||
| 0–2 | 18.4 | 10.3–26.5 | ||||
| ≥3 | 8.9 | 2.3–15.5 | ||||
CEA = carcinoembryonic antigen.