TABLE 3

COV (%) for Different Models

Model	Tumor	Muscle	Brain
COV K₁
2TM + v_b	24.30^*	39.90	28.06^*
Irreversible 2TM	26.91	30.13^*	31.01
1TM + v_b	34.06	37.69	34.71
COV k₂
2TM + v_b	61.58	51.72	51.57
Irreversible 2TM	61.98	48.32^*	46.15
1TM + v_b	40.31^*	49.64	40.58^*
COV k₃
2TM + v_b	39.10	52.22^*	25.20^*
Irreversible 2TM	31.93^*	64.88	31.16
COV k₄
2TM + v_b	Not applicable^†	159	Not applicable^†
COV K_i
Patlak	27.10	25.52	25.39
COV DV
Logan	39.39	36.62	41.31

↵* Lowest values.
↵† Not applicable because values are close to zero (<10⁻⁵).
2TM = 2-tissue model; +v_b = including contribution of the blood volume fraction; 1TM =1-tissue model.
Irreversible (k₄ = 0). Note that v_b is almost zero for all ROIs.