TABLE 2

In Silico Chemical and Biologic Properties for Prediction of SUVR in 10 Amyloid PET Radioligands

	In silico		Predicted from datasets
Radioligand	Vx (cm³/mol/100)	Lipophilicity (Moriguchi logP)	f_P	f_ND	K_D for simulation
¹¹C-PIB	1.88	2.40	0.303	0.152	1.40
¹¹C-BF-227	2.33	2.40	0.304	0.153	3.55
¹¹C-AZD2184	1.84	1.75	0.573	0.441	8.40
¹¹C-SB-13	1.86	3.23	0.135	0.040	2.43
¹⁸F-FACT	2.53	1.87	0.511	0.365	9.40
¹⁸F-florbetapir	2.80	2.52	0.270	0.126	3.72
¹⁸F-florbetaben	2.84	3.11	0.152	0.048	2.22
¹⁸F-flutemetamol	1.89	2.80	0.205	0.080	1.60
¹⁸F-FDDNP	2.31	2.89	0.187	0.068	3.90
¹⁸F-AZD4694	1.79	2.41	0.300	0.150	2.30