TABLE 3

Final Referral Diagnosis in Patients Included in Study

Final referral diagnosis18F-FDG PET/CT (n = 95)CT thorax/abdomen (n = 102)
Cancer*19 (20%)20 (20%)
 Lung cancer47
 Prostate cancer22
 Breast cancer20
 B-cell lymphoma11
 Colorectal cancer53
 Other malignant disease57
Infection5 (5%)5 (5%)
Autoimmune disease9 (9%)6 (6%)
Other diseases36 (38%)40 (39%)
 Gastric ulcer/gastritis115
 Liver steatosis/cirrhosis42
 COPD34
 Cardiovascular disease31
 Thyroid disease32
 MGUS41
 Other825
No disease found26 (27%)31 (30%)
  • * Malignant diagnosis was confirmed by tissue biopsies or bone marrow examination in 36 of these 39 patients before selection of cancer treatment strategy. The tissues biopsies or bone marrow examinations were obtained either in the DOC workup before referral (n = 13) or after referral from DOC.

  • Hepatitis C = hepatitis C RNA and antibody positive; pharyngitis = positive throat culture; HIV = antigen/antibody test positive; pneumonia = positive sputum culture; urinary tract infection = positive urinary culture; gastroenteritis = fecal swap polymerase chain reaction (PCR) positive for Clostridium difficile 027; and diverticulitis = clinical picture combined with CT of abdomen.

  • COPD = chronic obstructive pulmonary disease; MGUS = monoclonal gammopathy of undetermined significance.