TABLE 3

Voxel-by-Voxel Analyses

Region	Group 1 > group 2		K_e	P_FWE peak-voxel	T	x/y/z (mm)
Caudate nucleus left (df, 1,54)	PD	PSP	13	0.005	4.80	−14/4/20
	MSA-C	PSP	4	0.008	4.67	−12/18/12
Caudate nucleus right (df, 1,54)	PD	PSP	22	0.005	4.85	12/4/20
		MSA-P	2	0.024	4.30	16/0/24
	MSA-C	PSP	2	0.018	4.41	18/0/18
Posterior putamen left (df, 1,54)	MSA-C	PSP	41	0.004	4.69	−26/−2/4
		MSA-P	16	0.007	4.51	−26/−2/4
		PD	33	0.003	4.83	−26/−14/6
Posterior putamen right (df, 1,54)	PD	PSP	2	0.018	4.17	36/−16/−8
	MSA-C	PSP	30	0.004	4.73	28/−10/2
		MSA-P	28	0.001	5.22	28/−10/2
			13	0.002	4.88	32/−12/8
		PD	20	<0.001	5.73	28/−10/2
Hypothalamus^* (df, 1,43)	PD	PSP	17	<0.001	5.93	−4/0/−10
		MSA-P	6	0.002	4.79	−6/0/−10
	MSA-C	PSP	8	<0.001	5.47	−2/0/−8
		MSA-P	4	0.002	4.79	−6/0/−10

↵* For this analysis, patients not on SSRIs were included.
Difference between 2 diagnoses for specific cluster.
df =degrees of freedom; K_e = cluster extent in no. of voxels; P_FWE = familywise error–corrected P values; T = T statistic; x/y/z = location of significantly most different between-groups cluster from midpoint in millimeter.