Baseline Characteristics of 54 Included Patients
| Hypoxia, trial arm | No hypoxia | ||||
| Characteristic | Total (n = 34) | Boost (n = 24) | 66 Gy (n = 10) | 66 Gy (n = 20) | Total (n = 54) |
| Sex (n) | |||||
| Female | 6 | 4 | 2 | 1 | 7 |
| Male | 28 | 20 | 8 | 19 | 47 |
| Mean age ± SD (y) | 59.5 ± 8.6 | 60.5 ± 8.4 | 57.2 ± 9.2 | 61.4 ± 5.7 | 60.3 ± 7.7 |
| Mean height ± SD (cm) | 169.7 ± 9.3 | 171.1 ± 10.1 | 166.6 ± 6.1 | 170.3 ± 8.1 | 170.0 ± 8.8 |
| Mean weight ± SD (kg) | 73.2 ± 14.6 | 71.5 ± 12.3 | 77.2 ± 19.2 | 76.5 ± 12.1 | 74.4 ± 13.7 |
| Histology (n) | |||||
| SCC | 17 | 14 | 3 | 9 | 26 |
| ADC | 11 | 6 | 5 | 10 | 21 |
| Undifferentiated | 6 | 4 | 2 | 1 | 7 |
| Tumor stage (n) | |||||
| IB | 1 | 1 | — | 1 | 2 |
| IIA | — | — | 1 | 1 | |
| IIB | 2 | 1 | 1 | 0 | 2 |
| IIIA | 17 | 13 | 4 | 7 | 24 |
| IIIB | 13 | 8 | 5 | 11 | 24 |
| IV | 1 | 1 | — | — | 1 |
| Mean radiotherapy dose ± SD (Gy) | 73.9 ± 6.7 | 77.1 ± 5.2* | 66 ± 0 | 66 ± 0.4 | 71 ± 6.5 |
↵* Significantly different from 66-Gy group (P < 0.0001).
SCC = squamous cell carcinoma; ADC = adenocarcinoma.