Hypoxia (n = 34), trial arm | No hypoxia | ||||||||
Boost (n = 24) | 66 Gy (n = 10) | 66 Gy (n = 20) | |||||||
Acute adverse events | G1&2 | G3 | G4&5 | G1&2 | G3 | G4&5 | G1&2 | G3 | G4&5 |
Asthenia | 5 | 6 | 1 | 1 | |||||
Pain | 2 | 1 | 4 | ||||||
Thoracic pain | 5 | 2 | |||||||
Dysphagia | 17 | 1 | 6 | 3 | 1 | 11 | 4 | ||
Dyspnea | 1 | 3 | 1 | 6 | |||||
Hemoptysis | 1 | 1 (G5) | 1 | ||||||
Dry skin or pruritus | 15 | 1 | 1 | 9 | |||||
Anorexia | 3 | 2 | 3 | ||||||
Pneumonitis | 2 | 1 (G4) | 3 | ||||||
Cough or expectoration | 16 | 6 | 11 | ||||||
Hematologic toxicities | 2 | 1 | 1 | 1 | 4 | 2 | 1 (G4) | ||
Chemotherapy toxicities | 25 | 3 | 7 | 5 | 12 | 2 | 1 (G4) | ||
Other toxicities | 1 | 5 |