TABLE 2

Criteria for Classification of Inflammation and Osteogenesis Based on Changes in ¹⁸F-FDG and ¹⁸F-NaF Uptake

Group criteria	Stabilized inflammation/osteogenesis	Progressive inflammation/osteogenesis
TBR_max below cut-off at baseline and follow-up	TBR_max (baseline) ≤ 1.6/1.8	TBR_max (baseline) ≤ 1.6/1.8
	TBR_max (follow-up) ≤ 1.6/1.8	TBR_max (follow-up) ≤ 1.6/1.8
	Increasing TBR_max < 30% or decreasing TBR_max	Increasing TBR_max ≥ 30%
TBR_max above cut-off at baseline and follow-up	TBR_max (baseline) ≥ 1.6/1.8	TBR_max (baseline) ≥ 1.6/1.8
	TBR_max (follow-up) ≥ 1.6/1.8	TBR_max (follow-up) ≥ 1.6/1.8
	Decreasing TBR_max ≥ 30%	Decreasing TBR_max < 30% or increasing TBR_max
TBR_max above cut-off at baseline and below cut-off at follow-up	TBR_max (baseline) ≥ 1.6/1.8	TBR_max (baseline) ≥ 1.6/1.8
	TBR_max (follow-up) ≤ 1.6/1.8	TBR_max (follow-up) ≤ 1.6/1.8
	Decreasing TBR_max ≥ 10%	Decreasing TBR_max < 10%
TBR_max below cut-off at baseline and above cut-off at follow-up	TBR_max (baseline) ≤ 1.6/1.8	TBR_max (baseline) ≤ 1.6/1.8
	TBR_max (follow-up) ≥ 1.6/1.8	TBR_max (follow-up) ≥ 1.6/1.8
	Increasing TBR_max < 10%	Increasing TBR_max ≥ 10%

In TBR_max entries, first value is for ¹⁸F-FDG and second value is for ¹⁸F-NaF.