TABLE 1

Targeted Arterial Blood Gas Estimates and Hemodynamic Parameters

GroupSBP (mm Hg)HR (per min)RPP (mm Hg/min × 103)
Intact (n = 10)
PETCO2 (mm Hg)PETO2 (mm Hg)
 Adenosine37.5 ± 2.9119.9 ± 7.0128.6 ± 16.899.6 ± 34.7*12.3 ± 4.9*
 Hypercapnia60.6 ± 1.4*121.3 ± 5.8130.2 ± 14.381.8 ± 16.810.9 ± 2.4
 Rest36.9 ± 1.6118.3 ± 5.2121.2 ± 12.165.4 ± 15.28.2 ± 2.3
Stenosis (n = 7)
PaCO2 (mm Hg)PaO2 (mm Hg)
 Adenosine37.3 ± 2.2128.0 ± 4.9111.6 ± 32.2119.8 ± 26.9*14.9 ± 6.1*
 Hypercapnia61.6 ± 1.1*124.7 ± 5.6118.1 ± 25.2100.2 ± 22.812.5 ± 5.7*
 Rest35.9 ± 3.4126.1 ± 4.4118.0 ± 30.575.4 ± 17.08.9 ± 2.9
Caffeine (n = 5)
PaCO2 (mm Hg)PaO2 (mm Hg)
 Adenosine35.1 ± 0.6123.7 ± 3.0125.8 ± 8.065.4 ± 29.96.9 ± 1.7
 Hypercapnia59.9 ± 2.3*128.9 ± 6.8128.3 ± 11.669.8 ± 10.89.3 ± 3.6
 Rest34.5 ± 1.2125 ± 3.6124.0 ± 11.256.6 ± 23.27.1 ± 4.0
  • * P < 0.05 in comparison to rest values.

  • SBP = systolic arterial blood pressure; HR = heart rate; RPP = rate–pressure product (mean arterial pressure × HR).