TABLE 1

Criteria for Assessment of Renal Damage

GradeCriteria
0No irregularities
1Little dilatation of tubules; no basal membrane thickening
2Criteria as for grade 1, but more pronounced tubule dilatation, basal membrane thickening, and mitotic activity
3Shrinkage of small number of glomeruli; flat or lost tubule epithelium, strong tubule dilatation, and more pronounced basal membrane thickening
4Increased shrinkage of glomeruli leading to optical emptiness; strongly dilated tubules and signs of peripheral fibrosis