TABLE 1

Patient Characteristics (n = 74)

CharacteristicValue
Median age (y)61 (range, 28–82)
Sex
 Male53 (71.6)
 Female21 (28.4)
Histologic type
 Adenocarcinoma59 (79.7)
 Poorly cohesive carcinoma15 (20.3)
Differentiation (n = 59)
 Well to moderate33 (55.9)
 Poor26 (44.1)
HER2 status
 Negative60 (81.1)
 Positive14 (18.9)
Having primary lesion of the stomach
 No15 (20.3)
 Yes59* (79.7)
ECOG PS
 0, 165 (87.8)
 2, 39 (12.2)
Chemotherapy regimen
 FOLFOX31 (41.9)
 XELOX23 (31.1)
 XP+H14 (18.9)
 Other6 (8.1)
Median PFS (mo)8.0 (95% CI, 6.61–9.33)
Response rate (%)41
Disease control rate (%)70
Median overall survival (mo)17.4 (95% CI, 12.15–22.65)
  • * Number of undetected lesions in baseline PET was 3, and of reproducibly measurable lesions on CT scan it was 4.

  • ECOG PS = Eastern Cooperative Oncology Group Performance Status; FOLFOX = fluorouracil with leucovorin and oxaliplatin; XELOX = capecitabine and oxaliplatin; XP+H = capecitabine and cisplatin and trastuzumab.

  • Data in parentheses are percentages, unless otherwise indicated.