TABLE 1

Murine Endoscopic Index of Colitis Severity for Objective Quantification of Colonoscopic Findings

	Murine endoscopic index of colitis severity
Finding	0	1	2	3	Total
Thickening of the colon	Transparent	Moderate	Marked	Nontransparent	0–3
Changes of the vascular pattern	Normal	Moderate	Marked	Bleeding	0–3
Fibrin visible	None	Little	Marked	Extreme	0–3
Granularity of the mucosal surface	None	Moderate	Marked	Extreme	0–3
Stool consistency	Normal + solid	Still shaped	Unshaped	Spread	0–3
					Overall, 0–15

Changes in colon thickness, vasculature, fibrin deposition, mucosal granularity, and stool consistence were all noted and assigned a score based on severity. These scores were summed to yield an overall colitis severity score. Table was modified from Becker et al. (16).