Prostatectomy | Radiotherapy | |||
Characteristic | 68Ga | 18F | 68Ga | 18F |
No. of patients | 68 | 38 | 61 | 24 |
Age (y) | 70.1 ± 7.9 | 68.4 ± 7.0 | 72.1 ± 6.7 | 71.8 ± 8.5 |
Weight (kg) | 88.1 ± 16.2 | 87.9 ± 13.5 | 84.1 ± 12.5 | 90.5 ± 15.1 |
Height (cm) | 179 ± 6.9 | 179 ± 7.1 | 178 ± 6.5 | 180 ± 5.6 |
Median time between therapy and PSMA PET imaging (mo) | 61.2 ± 68.4 | 44.2 ± 49.7 | 55.3 ± 55.4 | 38.1 ± 38.3 |
PSA level (μg/L) | 2.5 ± 2.2 | 2.7 ± 3.8 | 8.5 ± 11.1 | 4.1 ± 7.5 |
Initial TNM staging with T ≤ 2 | 58.3% | 46.4% | 100% | 83.3% |
Gleason score | ||||
≤6 | 19.1% | 11.2% | 46.9% | 0% |
7 | 48.9% | 48.1% | 37.5% | 68.8% |
≥8 | 32.0% | 40.7% | 15.6% | 31.2% |
Patients were subdivided according to previous therapy (prostatectomy vs. radiotherapy) and tracer applied (68Ga: 68Ga-PSMA-HBED-CC vs. 18F: 18F-DCFPyL). On the basis of Gleason scores, patients were subdivided into moderately differentiated (≤6), moderately to poorly differentiated (=7), and poorly differentiated cases (≥8). Additionally, a fraction of patients initially displaying limited local tumor infiltration (TNM classification, T ≤ 2) is shown.