TABLE 1

PET-Derived Values

	Group^*			P
Parameter	Baseline (b)^†	Short-term treatment (st)^‡	Long-term treatment (lt)^§	ANOVA	Holm–Sidak method^\|\|
TBR_mean 18–61 min after injection	1.90 ± 0.10	1.89 ± 0.10	1.85 ± 0.06	NS (0.494)
TBR_max 18–61 min after injection	2.21 ± 0.26	2.17 ± 0.23	2.09 ± 0.15	NS (0.541)	b vs. lt: 0.002
AUC for tumor	94.97 ± 6.63	89.09 ± 6.50	83.28 ± 5.42	0.002	b vs. st: 0.061
Slope for tumor (SUV/h)	0.12 ± 0.07	0.09 ± 0.10	0.16 ± 0.10	NS (0.278)	st vs. lt: 0.100
Tumor volume (mm³)	44.14 ± 17.71	69.09 ± 87.61	39.38 ± 17.11	NS (0.305)

↵* Reported as mean ± SD.
↵† n = 8.
↵‡ n = 9.
↵§ n = 10.
↵|| P values from post hoc test (Holm–Sidak method) are reported when differences were significant.
NS = not significant; AUC = area under curve; slope = slope of time–activity curve for ¹⁸F-FET uptake 18–61 min after injection.