TABLE 4

Value of Each Indication in Changing Patients’ Management

Indication no.Clinical indicationNo change in managementChange in managementUnknown
18F-FDG PET/CT for diagnosis of tumor recurrence
 1Prior clinical suspicion of tumor recurrence32 (57.1)21 (37.5)3
 2Prior rising tumor markers or abnormal laboratory tests suggesting tumor recurrence18 (72.0)7 (28.0)0
 3Prior suggestive imaging (CT or MRI) for tumor recurrence38 (41.8)46 (50.5)7
 4Prior indeterminate or suggestive PET/CT scan for tumor recurrence100 (76.3)26 (19.8)5
18F-FDG PET/CT before starting therapy for tumor recurrence
 5Restaging after confirmation of tumor recurrence6 (33.3)12 (66.7)0
 6If extent of disease will alter therapy or if a new baseline was needed before change in therapy15 (32.6)28 (60.9)3
18F-FDG PET/CT to assess therapy response for tumor recurrence
 7Therapy response assessment of recurrence170 (63.9)83 (31.2)13
 8Intratreatment assessment of recurrence162 (77.1)44 (21.0)4
 9Follow-up scan to assess the previous equivocal response20 (64.5)9 (29.0)2
Follow-up 18F-FDG PET/CT after completion of treatment for tumor recurrence
 10Follow-up for stable disease107 (81.1)22 (16.7)3
 11Follow-up for disease progression56 (45.9)58 (47.5)8
 12Follow-up of disease in remission or per clinical trial protocol479 (90.2)30 (5.6)22
Total1,203 (72.5)386 (23.3)70
  • Data in parentheses are percentages.