TABLE 2

Univariate and Multivariate Analysis of Prognostic Factors for OS in Intrahepatic BCLC Stage C HCC Patients (n = 153)

UnivariateMultivariate
VariablenHRPHRP
Age (y)1.09 (0.77–1.54)0.64
 <5774
 ≥5779
Sex0.81 (0.48–1.37)0.48
 Male134
 Female19
Etiology0.90 (0.75–1.08)0.27
 HBV117
 HCV10
 Alcohol13
 Unknown13
Child–Pugh classification1.76 (1.17–2.66)0.0071.74 (1.14–2.67)0.011
 A122
 B31
AFP (ng/mL)1.09 (0.77–1.55)0.64
 <1,46677
 ≥1,46673
PIVKA-II (mAU/mL)1.53 (1.05–2.24)0.031.45 (0.99–2.12)0.053
 <1,20052
 ≥1,20092
Tumor size1.01 (0.71–1.44)0.96
 <10.387
 ≥10.366
Tumor number1.12 (0.79–1.59)0.51
 <477
 ≥476
TLR1.85 (1.30–2.65)0.0011.89 (1.30–2.73)0.001
 <3.069
 ≥3.084

  • HR = hazard ratio; HBV = hepatitis B virus; HCV = hepatitis C virus.

  • Data in parentheses are 95% confidence intervals.