TABLE 2

Interim Assessment

	CT-2 (n = 56)		PET-2 (RIW) (n = 56)			PET-2 (DC) (n = 52)
Parameter	CR	No CR	Positive	Negative	P^*	Positive	Negative	P^†
Relapse (n = 4)	1	3	1	3		0	4
Remission (n = 52)^‡	21	31	20	32		4	44
Sensitivity (%)	75 (21.9–98.6)		25 (13.1–78)		0.18	0 (0–60.4)		0.04
Specificity (%)	40.3 (27.3–54.8)		61.5 (47–74.3)		0.03	91.4 (78.7–97.2)		<0.0001
PPV (%)	8.8 (2.3–24.8)		4.7 (0.2–25.8)		0.57	0 (0–60.4)		0.54
NPV (%)	95.4 (75.1–99.7)		91.4 (75.8–97.7)		0.39	91.4 (78.7–97.2)		0.4

↵* P value calculated for PET-2 (RIW) vs. CT-2.
↵† P value calculated for PET-2 (DC) vs. CT-2.
↵‡ 1 patient who died of pulmonary toxicity (patient 57) was excluded from above analysis.
Data in parentheses are 95% confidence intervals.