Kinetic parameter estimation error (ε) % | ||||
Preclinical | Clinical | |||
Kinetic parameter | Median | Interquartile range | Median | Interquartile range |
K1 | −0.003 | −0.020 to 0.012 | 0.012 | −0.073 to 0.116 |
k2 | −0.040 | −0.180 to 0.071 | 0.050 | −0.140 to 0.287 |
k3 | −0.121 | −0.649 to 0.213 | 0.049 | −0.260 to 0.387 |
Ki | −0.033 | −0.385 to 0.091 | 0.000 | −0.143 to 0.165 |