TABLE 1

Subject Demographics and Clinical Features

DemographicPCA (n = 16)DLB (n = 13)P
Sex (% female)7 (44%)2 (15%)0.10
Age at onset (y)60.5 (54.0–63.8)66 (61.5–70.0)0.005
Age at 18F-FDG (y)64.0 (58.0–70.0)68.0 (64.0–71.5)0.15
Disease duration4 (3.3–6.5)3 (2–4)0.006
Handedness (right)15 (94%)13 (100%)0.27
Mini-Mental State Examination (/30)25.5 (21.8–28.0)25.0 (18.5–25.8)0.32
Clinical features (%)
 Optic ataxia3 (21%)*0 (0%)0.04
 Simultanagnosia12 (86%)*0 (0%)<0.0001
 Oculomotor apraxia7 (50%)*0 (0%)0.001
 Dysgraphia10 (63%)0 (0%)<0.0001
 Hallucinations4 (25%)7 (54%)0.11
 Fluctuations0 (0%)12 (92%)<0.0001
 Parkinsonism2 (12.5%)13 (100%)<0.0001
 Rapid eye movement sleep behavior disorder3 (19%)10 (77%)0.001
  • * Clinical features were assessed in 14 PCA subjects.

  • Data are median, with interquartile range in parentheses, or number, with percentage in parentheses.