Subject Demographics and Clinical Features
Demographic | PCA (n = 16) | DLB (n = 13) | P |
Sex (% female) | 7 (44%) | 2 (15%) | 0.10 |
Age at onset (y) | 60.5 (54.0–63.8) | 66 (61.5–70.0) | 0.005 |
Age at 18F-FDG (y) | 64.0 (58.0–70.0) | 68.0 (64.0–71.5) | 0.15 |
Disease duration | 4 (3.3–6.5) | 3 (2–4) | 0.006 |
Handedness (right) | 15 (94%) | 13 (100%) | 0.27 |
Mini-Mental State Examination (/30) | 25.5 (21.8–28.0) | 25.0 (18.5–25.8) | 0.32 |
Clinical features (%) | |||
Optic ataxia | 3 (21%)* | 0 (0%) | 0.04 |
Simultanagnosia | 12 (86%)* | 0 (0%) | <0.0001 |
Oculomotor apraxia | 7 (50%)* | 0 (0%) | 0.001 |
Dysgraphia | 10 (63%) | 0 (0%) | <0.0001 |
Hallucinations | 4 (25%) | 7 (54%) | 0.11 |
Fluctuations | 0 (0%) | 12 (92%) | <0.0001 |
Parkinsonism | 2 (12.5%) | 13 (100%) | <0.0001 |
Rapid eye movement sleep behavior disorder | 3 (19%) | 10 (77%) | 0.001 |
↵* Clinical features were assessed in 14 PCA subjects.
Data are median, with interquartile range in parentheses, or number, with percentage in parentheses.