TABLE 2

Regional ¹⁸F-FDG SUVRs

Region	Controls	PCA	DLB	PCA vs. DLB P
Occipital lobe
Lateral occipital gyrus	1.78 (1.62–1.83)	1.26 (1.19–1.46)^*	1.31 (1.25–1.41)^*	0.47
Cuneus	1.95 (1.75–2.02)	1.60 (1.51–1.82)^*	1.61 (1.48–1.66)^*	0.71
Calcarine gyrus	2.02 (1.89–2.13)	1.80 (1.68–1.97)^*	1.65 (1.52–1.75)^*	0.01
Lingual gyrus	1.84 (1.68–1.91)	1.64 (1.50–1.75)^*	1.46 (1.43–1.53)^*	0.02
Occipital asymmetry^†	0.02 (0.01–0.03)	0.12 (0.07–0.14)^*	0.06 (0.01–0.10)	0.02
Parietal lobe
Inferior parietal lobe	2.00 (1.89–2.10)	1.51 (1.33–1.66)^*	1.45 (1.31–1.65)^*	0.84
Superior parietal lobe	2.01 (1.94–2.16)	1.55 (1.40–1.62)^*	1.51 (1.38–1.68)^*	0.97
Supramarginal gyrus	1.75 (1.69–1.84)	1.46 (1.33–1.62)^*	1.43 (1.36–1.52)^*	0.28
Angular gyrus	1.92 (1.81–2.03)	1.34 (1.26–1.49)^*	1.33 (1.19–1.40)^*	0.34
Precuneus	1.98 (1.82–2.07)	1.51 (1.37–1.65)^*	1.51 (1.37–1.57)^*	0.87
Posterior cingulate	1.72 (1.59–1.83)	1.44 (1.33–1.61)^*	1.46 (1.41–1.59)^*	0.68
Parietal asymmetry^†	0.04 (0.02–0.07)	0.14 (0.09–0.18)^*	0.05 (0.04–0.07)	0.005
Temporal lobe
Temporal pole	1.45 (1.40–1.51)	1.43 (1.34–1.52)	1.34 (1.30–1.37)^*	0.007
Inferior temporal gyrus	1.62 (1.57–1.68)	1.33 (1.24–1.45)^*	1.29 (1.25–1.35)^*	0.32
Middle temporal gyrus	1.67 (1.60–1.73)	1.34 (1.23–1.45)^*	1.28 (1.20–1.42)^*	0.48
Superior temporal gyrus	1.68 (1.60–1.75)	1.51 (1.42–1.59)^*	1.44 (1.39–1.53)^*	0.17
Hippocampus	1.23 (1.20–1.26)	1.19 (1.14–1.32)	1.25 (1.18–1.27)	0.65
Parahippocampal gyrus	1.32 (1.30–1.40)	1.27 (1.17–1.37)	1.23 (1.18–1.27)^*	0.43
Fusiform gyrus	1.52 (1.47–1.60)	1.27 (1.23–1.41)^*	1.29 (1.27–1.37)^*	0.59
Temporal asymmetry^†	0.02 (0.01–0.03)	0.06 (0.03–0.09)^*	0.04 (0.01–0.06)	0.11
Frontal lobe
Orbitofrontal cortex	1.82 (1.75–1.91)	1.77 (1.66–1.87)	1.64 (1.56–1.68)^*	0.003
Prefrontal cortex	1.85 (1.78–1.20)	1.73 (1.63–1.83)^*	1.65 (1.52–1.71)^*	0.04
Frontal asymmetry^†	0.04 (0.03–0.06)	0.03 (0.02–0.08)	0.04 (0.02–0.09)	0.65
Subcortical
Caudate	1.55 (1.53–1.60)	1.48 (1.42–1.59)	1.40 (1.35–1.43)^*	0.02
Putamen	1.55 (1.49–1.61)	1.49 (1.39–1.56)^*	1.45 (1.41–1.52)^*	0.45
Thalamus	1.59 (1.53–1.67)	1.47 (1.42–1.52)^*	1.43 (1.40–1.46)^*	0.13
Subcortical asymmetry^†	0.03 (0.02–0.04)	0.03 (0.01–0.04)	0.02 (0.01–0.05)	0.77
CIS	0.91 (0.87–0.93)	0.91 (0.86–0.98)	0.94 (0.88–1.03)	0.43

↵* Significant difference from controls at P < 0.05.
↵† Asymmetry scores calculated as absolute difference between left and right hemisphere SUVRs.
Data shown are median, with interquartile range in parentheses.