Number or mean ± SD | |||
Characteristic | Chemotherapy | Endocrine therapy | P |
Age (y) | 58.4 (5.4) | 60.9 (5.3) | 0.24 |
Histology | 0.48 | ||
Invasive ductal carcinoma | 13 | 11 | |
Invasive lobular carcinoma | 0 | 2 | |
Histologic grade | 0.22 | ||
2 | 13 | 10 | |
3 | 0 | 3 | |
ER (Allred score) | 0.83 | ||
6 | 1 | 1 | |
7 | 1 | 2 | |
8 | 11 | 10 | |
Progesterone receptor | 0.42 | ||
Positive | 9 | 7 | |
Negative | 4 | 6 | |
HER2 | 0.30 | ||
Positive | 1 | 1 | |
Equivocal | 3 | 1 | |
Negative | 9 | 11 | |
18F-FES PET/CT | 0.48 | ||
Visual analysis | |||
Negative | 2 | 0 | |
Positive | 11 | 13 | |
SUVmax | 6.6 ± 3.9 | 12.0 ± 9.2 | 0.06 |
Pathologic response (Miller–Payne grade)* | 0.12 | ||
2 | 4 | 9 | |
3 | 6 | 4 | |
4 | 0 | 0 | |
5 | 2 | 0 | |
% reduction in tumor cellularity* | 50.8 ± 35.0 | 22.7 ± 17.4 | 0.02 |
↵* Pathologic response after NC was analyzed in 12 patients.