TABLE 1

Baseline Characteristics of Patients and Pathologic Response After Neoadjuvant Therapy

Number or mean ± SD
CharacteristicChemotherapyEndocrine therapyP
Age (y)58.4 (5.4)60.9 (5.3)0.24
Histology0.48
 Invasive ductal carcinoma1311
 Invasive lobular carcinoma02
Histologic grade0.22
 21310
 303
ER (Allred score)0.83
 611
 712
 81110
Progesterone receptor0.42
 Positive97
 Negative46
HER20.30
 Positive11
 Equivocal31
 Negative911
18F-FES PET/CT0.48
 Visual analysis
  Negative20
  Positive1113
 SUVmax6.6 ± 3.912.0 ± 9.20.06
Pathologic response (Miller–Payne grade)*0.12
 249
 364
 400
 520
% reduction in tumor cellularity*50.8 ± 35.022.7 ± 17.40.02
  • * Pathologic response after NC was analyzed in 12 patients.