VT for Striatum, Hippocampus, Midbrain, and Cerebellum Using 1TCM, 2TCM, and Logan Graphical Analysis
| 18F-FPSCH | 18F-FESCH | ||||||
| Region | Group | 1TCM | 2TCM | Logan | 1TCM | 2TCM | Logan |
| STR | Control | 3.69 ± 1.11 (30.00%) | 3.72 ± 1.10 (29.53%) | 3.52 ± 1.11 (31.62%) | 4.80 ± 1.69 (35.21%) | 5.00 ± 1.96 (39.13%) | 4.66 ± 1.95 (41.96%) |
| Pretreated | 0.98 ± 0.38 (38.14%) | 1.00 ± 0.39 (38.70%) | 0.96 ± 0.32 (33.46%) | 1.00 ± 0.28 (28.18%) | 1.22 ± 0.26 (21.71%) | 1.19 ± 0.20 (17.03%) | |
| HC | Control | 1.13 ± 0.29 (25.54%) | 1.14 ± 0.32 (27.92%) | 1.13 ± 0.26 (22.89%) | 1.16 ± 0.21 (18.40%) | 1.29 ± 0.29 (22.72%) | 1.25 ± 0.30 (24.20%) |
| Pretreated | 0.90 ± 0.35 (39.41%) | 0.91 ± 0.37 (40.73%) | 0.98 ± 0.35 (35.37%) | 0.75 ± 0.19 (25.03%) | 1.10 ± 0.28 (25.56%) | 1.00 ± 0.20 (19.66%) | |
| MB | Control | 1.16 ± 0.27 (22.96%) | 1.17 ± 0.26 (22.34%) | 1.15 ± 0.23 (20.39%) | 1.15 ± 0.29 (25.13%) | 1.26 ± 0.40 (31.43%) | 1.22 ± 0.37 (30.26%) |
| Pretreated | 0.97 ± 0.39 (40.16%) | 0.99 ± 0.40 (40.44%) | 1.07 ± 0.49 (45.45%) | 0.83 ± 0.15 (17.78%) | 1.18 ± 0.41 (34.63%) | 1.05 ± 0.15 (14.63%) | |
| CB | Control | 1.15 ± 0.29 (25.63%) | 1.14 ± 0.29 (25.31%) | 1.07 ± 0.29 (26.69%) | 1.14 ± 0.27 (23.79%) | 1.25 ± 0.34 (27.50%) | 1.22 ± 0.35 (28.67%) |
| Pretreated | 0.95 ± 0.37 (38.85%) | 0.97 ± 0.39 (39.90%) | 0.96 ± 0.32 (33.44%) | 0.82 ± 0.13 (15.62%) | 1.40 ± 0.49 (35.11%) | 1.14 ± 0.13 (11.47%) | |
CB = cerebellum; HC = hippocampus; MB = midbrain; STR = striatum.
Data are mean ± SD, followed by coefficient of variation in parentheses.